Michio Hongo Selected Research

Rabeprazole (Aciphex)

1/2017	Therapeutic Response to Twice-daily Rabeprazole on Health-related Quality of Life and Symptoms in Patients with Refractory Reflux Esophagitis: A Multicenter Observational Study.
5/2012	Symptoms and quality of life in underweight gastroesophageal reflux disease patients and therapeutic responses to proton pump inhibitors.
4/2012	Efficacy of twice-daily rabeprazole for reflux esophagitis patients refractory to standard once-daily administration of PPI: the Japan-based TWICE study.
11/2011	Investigation of pretreatment prediction of proton pump inhibitor (PPI)-resistant patients with gastroesophageal reflux disease and the dose escalation challenge of PPIs-TORNADO study: a multicenter prospective study by the Acid-Related Symptom Research Group in Japan.
8/2011	Acid-suppressive effect of rabeprazole 5 mg and 10 mg once daily by 24-hour esophageal pH monitoring in patients with non-erosive reflux disease in Japan: a multicenter, randomized, parallel-group, double-blind pharmacodynamic study.
3/2011	Effect of rabeprazole treatment on health-related quality of life and symptoms in patients with reflux esophagitis: a prospective multicenter observational study in Japan.
1/2011	Safety and efficacy of long-term maintenance therapy with oral dose of rabeprazole 10 mg once daily in Japanese patients with reflux esophagitis.
12/2010	Risk factors for relapse of erosive GERD during long-term maintenance treatment with proton pump inhibitor: a prospective multicenter study in Japan.
12/2008	It is possible to classify non-erosive reflux disease (NERD) patients into endoscopically normal groups and minimal change groups by subjective symptoms and responsiveness to rabeprazole -- a report from a study with Japanese patients.

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Michio Hongo Research Topics

Disease

11	Osteoporosis 07/2022 - 08/2012
11	Gastroesophageal Reflux (GERD) 12/2020 - 01/2008
11	Peptic Esophagitis (Reflux Esophagitis) 01/2017 - 01/2008
10	Neoplasms (Cancer) 12/2020 - 07/2007
7	Kyphosis 01/2021 - 01/2002
6	Non-Erosive Reflux Disease 08/2016 - 12/2008
5	Pain (Aches) 01/2021 - 05/2006
4	Infections 12/2020 - 06/2010
4	Osteoporotic Fractures 01/2020 - 01/2002
4	Congenital Abnormalities (Deformity) 06/2018 - 01/2010
4	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 02/2015 - 06/2006
4	Heartburn (Pyrosis) 05/2012 - 10/2007
3	Lordosis 01/2020 - 06/2013
3	Spinal Stenosis (Stenosis, Spinal) 06/2018 - 03/2014
2	Inflammation (Inflammations) 12/2020 - 06/2006
2	Bone Resorption 10/2020 - 07/2009
2	Meningioma (Meningiomas) 01/2020 - 07/2015
2	Low Back Pain (Lumbago) 01/2020 - 01/2002
2	Deglutition Disorders (Dysphagia) 01/2020 - 11/2016
2	Back Pain (Backache) 10/2019 - 07/2015
2	Spinal Cord Neoplasms (Spinal Cord Tumors) 06/2018 - 11/2010
2	Metabolic Bone Diseases (Osteopenia) 01/2018 - 12/2017
2	Hypesthesia (Numbness) 01/2018 - 01/2002
2	Constipation 01/2018 - 02/2015
2	Surgical Wound Infection 01/2018 - 12/2017
2	Body Weight (Weight, Body) 12/2017 - 01/2010
2	Spinal Curvatures (Spinal Curvature) 03/2015 - 01/2010
2	Scoliosis 03/2015 - 08/2009
2	Postmenopausal Osteoporosis 05/2014 - 12/2005
2	Hemorrhage 03/2013 - 07/2007
2	Dyspepsia (Indigestion) 06/2012 - 01/2012
2	Abdominal Pain (Pain, Abdominal) 04/2011 - 01/2008
2	Hematoma 11/2010 - 09/2006
2	Lipomatosis 01/2006 - 01/2002
1	Chronic Renal Insufficiency 07/2022
1	Drug-Related Side Effects and Adverse Reactions 07/2022
1	Hypocalcemia 07/2022
1	Breast Neoplasms (Breast Cancer) 03/2022
1	Neoplasm Metastasis (Metastasis) 03/2022
1	Sarcopenia 03/2021
1	Spinal Diseases (Disease, Spinal) 01/2021
1	Ulcer 12/2020
1	Central Nervous System Diseases (CNS Diseases) 12/2020
1	Dementia (Dementias) 12/2020
1	Peptic Ulcer (Peptic Ulcers) 12/2020
1	Pseudarthrosis (Pseudoarthrosis) 07/2020
1	Tibial Fractures (Fracture, Tibial) 05/2020
1	Periprosthetic Fractures 05/2020
1	Osteonecrosis (Kienbock's Disease) 01/2020
1	Necrosis 01/2020
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 11/2019
1	Heart Arrest (Cardiac Arrest) 11/2019
1	Air Embolism (Gas Embolism) 11/2019
1	Spondylolisthesis 10/2019
1	Parkinson Disease (Parkinson's Disease) 03/2019
1	Compression Fractures (Compression Fracture) 01/2019

Drug/Important Bio-Agent (IBA)

13	Proton Pump InhibitorsIBA 01/2017 - 05/2009
9	Rabeprazole (Aciphex)FDA Link 01/2017 - 12/2008
7	Diphosphonates (Bisphosphonates)IBA 03/2022 - 07/2009
7	AcidsIBA 12/2020 - 05/2004
5	BESIBA 03/2021 - 12/2005
4	Teriparatide (Parathar)FDA Link 07/2020 - 08/2016
3	Alendronate (Alendronate Sodium)FDA LinkGeneric 02/2019 - 07/2009
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 03/2013
2	Denosumab FDA Link 07/2022 - 10/2020
2	Pharmaceutical PreparationsIBA 12/2020 - 08/2016
2	GlucocorticoidsIBA 07/2020 - 12/2017
2	Durapatite (Hydroxylapatite)IBA 01/2020 - 06/2018
2	Messenger RNA (mRNA)IBA 01/2018 - 03/2015
2	Vitamin D FDA LinkGeneric 01/2018 - 09/2016
2	RNA (Ribonucleic Acid)IBA 01/2018 - 03/2015
2	Histamine (Histamine Dihydrochloride)FDA Link 08/2016 - 01/2008
2	Risedronic Acid (Actonel)FDA LinkGeneric 07/2015 - 05/2014
2	Vitamin K FDA Link 05/2014 - 07/2009
2	OsteocalcinIBA 05/2014 - 07/2009
2	GastrinsIBA 01/2011 - 06/2010
1	ProcollagenIBA 07/2022
1	CalciumIBA 07/2022
1	Tartrate-Resistant Acid PhosphataseIBA 07/2022
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2020
1	Ibandronic Acid (Boniva)FDA Link 02/2019

Therapy/Procedure

20	Therapeutics 12/2020 - 01/2002
8	Decompression 01/2021 - 01/2003
7	Laminectomy 11/2019 - 09/2006
5	Laminoplasty 01/2020 - 11/2010
3	Activities of Daily Living (ADL) 01/2020 - 01/2017
3	Aftercare (After-Treatment) 08/2014 - 01/2011
2	Operative Surgical Procedures 01/2021 - 09/2012
2	Subcutaneous Injections 01/2021 - 12/2017
2	Spinal Fusion (Spondylosyndesis) 03/2019 - 01/2019
2	Surgical Decompression 04/2010 - 01/2003
1	Drug Therapy (Chemotherapy) 03/2021
1	Bone Transplantation (Bone Grafting) 10/2020
1	Arthroplasty 05/2020
1	External Fixators 05/2020
1	Enteral Nutrition (Feeding, Tube) 01/2020
1	Surgical Instruments (Clip) 11/2019
1	Cardiopulmonary Resuscitation (CPR) 11/2019
1	Operative Time 10/2019
1	Reoperation 10/2019